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Caco-2 cells were cultured in bioreactors and in Transwells additionally the basolateral transportation of rhodamine-123 had been assessed in the two systems as a function associated with the P-gp activity. Experiments were done with and without pre-treatment associated with cells with an extract of curcumin or an arylmethyloxy-phenyl derivative to gauge the inhibitory effect of the all-natural material with regards to a synthetic substance. The outcomes suggested that the P-gp activity for the
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