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To assess the contribution of thyroid hormone signalling via integrin αvβ3, expressed on numerous tumour cells, endothelial cells, and stromal cells, to tumour development, we compared the effects of thyroid hormones vs tetrac, a particular inhibitor of thyroid hormones activity at integrin αvβ3, in two murine xenograft tumour models with and without integrin αvβ3 appearance. Integrin αvβ3-positive real human anaplastic thyroid cancer tumors cells SW1736 and integrin αvβ3-negative peoples hepatocellular carci