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More, in-vitro experiments were performed to evaluate the cholinesterase inhibitory activity and reduced total of amyloid-beta (Aβ1-42) plaques potency, PAMPA assay permeability, and antioxidant task, these results suggested that compound VA10 can be a lead molecule among all the synthesized analogs. The substance VA10 binds towards AChE peripheral anionic website (PAS) property was founded through propidium iodide displacement assay. Additionally, VA10 showed no notable cytotoxicity and exhibi

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