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ADHD Medications For Adults Stimulants are able to regulate the levels of chemical messengers that regulate attention in the brain. They are considered to be the first line of treatment for ADHD. Although they are not in any way habit-forming, they can trigger negative side effects, such as headaches and difficulty sleeping. To decrease impulsivity or hyperactivity, your doctor may prescribe guanfacine under the brand names Tenex or Intuniv (Catapres). These medications are more effective than stimul