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To assess infectious and thrombotic complications of peripherally inserted central catheters (PICCs) in adults. A 5-year prospective cohort study. Tertiary-care teaching hospital in Seville, Spain. Adult patients undergoing PICC insertion. Catheter-associated bloodstream infection (CABSI) including catheter-related bloodstream infection (CRBSI), primary bacteremia (P, and upper extremity deep vein thrombosis (UEDVT) were recorded. Independent predictors of complications were assessed by multivariate analysis. In total, 1,142 PICCs wer
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