https://www.selleckchem.com/pr....oducts/piperlongumin
Antimicrobial resistance in cystic fibrosis (CF) Pseudomonas aeruginosa airway infection is complex and often attributed to chromosomal mutations. How these mutations emerge in specific strains or whether particular gene mutations are clinically informative is unclear. This study focused on oprD, which encodes an outer membrane porin associated with carbapenem resistance when it is downregulated or inactivated. Determine how mutations in oprD emerge in two prevalent Australian shared CF strains of P. aeruginosa and their clinical