https://www.selleckchem.com/pr....oducts/pf-06700841.h
There was no significant treatment effect on peak PCWP/CI (-0.13mmHg/l/min/m ; 95% confidence interval-1.60 to 1.34mmHg/l/min/m ; p=0.86). Considering hemodynamics over the full range of exercise loads, PCWP was significantly reduced (-2.40mmHg; 95% confidence interval-3.96 to-0.84mmHg; p=0.003), but not CI (-0.09 l/min/m ; 95% confidence interval-0.14 to 0.32 l/min/m ; p=0.448) by empagliflozin. This was consistent among patients with and without type 2 diabetes. Among patients with stable HFrEF, empagliflozin for 12weeks reduced P