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Medication For ADHD - What Are the Side Effects? Many people suffering from ADHD experience improvements in their symptoms through medication. Every person's reaction to medication is different, and side effects are sometimes problematic. Methylphenidate is a stimulant. is a stimulant that increases levels of a chemical within the brain that assists in controlling the behavior and attention. Stimulant drugs Stimulant medication improves attention and concentration for 70% to 80%