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But, the drawbacks among these conjugation practices range from the importance of a big more than conjugation building block, comparably reasonable reaction rates and restricted stability of FGly-containing proteins. Consequently, functionalized clickable HIPS and tandem Knoevenagel building blocks had been synthesized, conjugated to small proteins (DARPins) and subsequently connected to strained alkyne-containing payloads for protein labeling. This process allowed th

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