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We confirmed the formerly observed upsurge in the levels of several pro-inflammatory cytokines, such as for example TNF-α and IL-6, and discovered that several other cytokines, right or indirectly involved with inflammation (such as for example IFN-α, IL-23, CCL-5), had been current at higher amounts in centenarians. We didn't observe any escalation in the levels of anti-inflammatory cytokines, using the significant exclusion regarding the Th2-shifting cytokine IL-19. No appropriate distinctio
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