https://micrornaassay.com/step....wise-placement-of-co
The basic type of SCD physiology states that vaso-occlusion takes place when hemoglobin S-containing purple blood cells (RBC) undergo sickling before they escape the capillary into a larger vessel. We now have shown that emotional tension, pain and cool, and events reported by patients to trigger SCD vaso-occlusive crisis (VOC), cause rapid and considerable decline in blood circulation, reducing the probability that RBC could transit the microvasculature before sickling
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