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How Does ADHD Medication Work? When a neuron sends a message to another, it makes use of neurotransmitters, chemicals. They need to cross a tiny gap called the synapse. Some ADHD medications increase the efficiency of these messages. They either help neurons release neurotransmitters faster or slow the process of reuptake (called Reuptake inhibitors). Doctors place patients with ADHD on a low dose of medication, and then monitor their reactions. They adjust the dosage over time to find a "sweet spot" -the lowest dose that shows noticeable i
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