https://www.selleckchem.com/pr....oducts/Obatoclax-Mes
ience may have a competitive edge in attracting applicants to their programs.BACKGROUND Neoadjuvant chemoradiation for locally advanced rectal cancer combining 5FU to radiation increases tumor regression compared to radiation alone. However, it occurs at the cost of significant treatment-related toxicity. Patients with rectal cancer using metformin have been associated with improved response to radiotherapy. OBJECTIVE To evaluate the radiosensitizing effects of metformin in vitro and in vivo and compare it to standard combina