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Groups comprised 11 mice each, including an untreated normal and untreated diseased control group (7 groups total). CsA 0.09% sol twice daily significantly increased tear volume on day 30, 45, and 60 vs CsA 0.05% eml ( 0.05, 0.001, 0.001, respectively) and vs CsA 0.1% eml on day 60 ( 0.05); CsA 0.09% sol once daily significantly increased tear volume on day 45 vs CsA 0.05% eml ( 0.05). Goblet cell density significantly increased with CsA 0.09% sol twice daily vs placebo and NOD control ( 0.01 both). There was no s

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