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Moreover, salidroside improved spatial learning and memory in rats with vascular dementia. The therapeutic effect of salidroside is probably based on its antioxidant effects and inhibition of caspase-3-mediated apoptosis via suppression of p38 MAPK signaling pathway.We analyzed cytotoxicity of water-soluble potassium salts of (+)- and (-) usnic acid (UA) for ciliates P. caudatum. The median lethal concentrations for (+)- and (-) enantiomers did not significantly differ and were 7.5±0.5 and 6.7±0.4, respectively. In a concentration of 8
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