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The Most Effective ADHD Medication For Adults Adults suffering from ADHD are usually prescribed stimulants. They assist in adjusting the levels of two chemical messengers in the brain that regulate the ability to pay attention. The most effective adhd medication for adults is Strattera (atomoxetine). It is a pill or oral capsule that can be taken either with or without food. Most people find it effective. It also lasts longer than the more sedatives, like amphetamine or methylphenidate. 1. Strattera S

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