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Non Prescription ADHD Medication For many people with ADHD, the first step to treat is medication. Medication can help improve concentration and reduce the tendency to be impulsive. The most frequently used medication for ADHD is stimulants. They work by increasing the levels of neurotransmitters like dopamine and norepinephrine in the brain. They are available in short-acting as well as long-acting varieties. 1. Stimulants Many people with ADHD take stimulant medications, which increase d