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first study to examine the efficacy of MBSR in modifying affective and somatic symptoms based on ELAb status, and provides evidence for considering ELAb in tailoring treatment approaches.Trial RegistrationClinicalTrials.gov Identifier NCT01995916; https//clinicaltrials.gov/ct2/show/NCT01995916. Xeroderma pigmentosum (XP) is an extreme hypersensitivity to sunlight causing skin freckling and pigmentary changes because of defective DNA repair mechanisms. The purpose of this article is to evaluate the spectrum of ocular and systemic features

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