https://www.selleckchem.com/products/tpi-1.html
The combination therapy also induced a significantly greater inhibitory effect on tumor growth in xenograft model in mice transplanted with either 11-18 or HCC827 cells compared with erlotinib alone or T-DM1 alone. No body weight loss was observed in these mice. These results suggested that the combination therapy with EGFR-TKI and T-DM1 might be a potentially promising strategy for treating lung cancer harboring EGFR mutations.The canonical Wnt signaling pathway plays a crucial role in embryonic development, tissue homeostasis and cancer
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