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Herein, we tested the theory that numerous RCD paths underlie microglial pyroptosis when you look at the framework of neuroinflammation. Activation of executioner caspases-3/7, widely considered key mediators of apoptosis, contributed to GSDMD-associated microglial pyroptosis under neuroinflammatory circumstances. Collectively, these observations highlight the convergence of different cell death paths during neuroinflammation and gives brand-new therapeutic possibilities in neuroinflammat
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