https://www.selleckchem.com/pr....oducts/gw806742x.htm
troduction of a nitric oxide donor. Early disruption of PDZ2 domain-mediated protein-protein interactions mimics isoflurane in decreasing mushroom spine density and causing learning and memory deficits in mice. Prevention of the decrease in mushroom spine density with a nitric oxide donor supports a role for neuronal nitric oxide synthase pathway in mediating this cellular change associated with cognitive impairment. A fundamental goal of continuous process improvement programs is to evaluate and improve the ratio of actual to expecte
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