Among the tumor disease models, the mostly used is the mouse xenograft tumor model that utilizes specific mice, such as SCID, NSG, B-NDG mice, and other conventional immunodeficiency or severe immunodeficiency mice, which cannot produce immune attacks on foreign cells.

* CDX (Cell-line-derived Xenograft) model: Standardized cancer cell lines are used for modeling. The cells are easy to obtain but have drawbacks that they cannot represent the original clinical tumor.
* PDX (Patient-derived Xenograft) model: Tumor tissue or cells obtained from tumor patients with the characteristics of clinical tumors.
For more: https://www.creative-biolabs.c....om/immuno-oncology/p