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https://www.selleckchem.com/pr....oducts/alofanib-rpt8
69, 95% confidence interval [CI] 1.01-2.84), depression (OR 1.94, 95% CI 1.28-2.95) and frailty (OR 2.55, 95% CI 1.55-4.19) were significantly associated with the composite endpoint of death or clinically relevant bleeding. After multivariable adjustment, depression (OR 1.79, 95% CI 1.09-2.93) and frailty (OR 2.83, 95% CI 1.55-5.17) were significantly associated with clinically relevant bleeding. Social isolation, depression, and frailty were prognostic of dying or experiencing clinically relevant bleeding during the coming year

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