https://www.selleckchem.com/pr....oducts/chir-99021-ct
The pre-storage LR did not affect the levels of PLT activation markers. The enhanced PLT activation was presumably mediated by free hemoglobin and/or the products of its breakdown, accumulating in the PRBC milieu, and their ability to trigger the ROS generation. Additionally, collagen-induced PLT aggregation was increased by low molecular weight substances possibly derived from the residual leukocytes and PLTs present in PRBCs. Transfusion of aged PRBCs may result in the hyper-activity of PLTs, which, at least in part, co
Like
Comment
Share
