https://www.selleckchem.com/pr....oducts/orforglipron-
Expression of CD44 receptor was not affected by miR-146a treatments, while TLR-4 expression and NF-kB activation were modified. We concluded that up-regulation of miR146a occurred in 6-mer HA-induced inflammation response may reduce the inflammatory cascade by modulating TLR-4 and NF-kB activation. These results could be useful in develop new therapeutic strategies with the aim to reduce OA and RA incidence. These results could be useful in develop new therapeutic strategies with the aim to reduce OA and RA incidence. Use
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