https://www.selleckchem.com/pr....oducts/sb-204990.htm
The volume and the volume-increasing rate increased by 3.665 cm3, 0.285% (p 150 cm2, as a proxy for an extremely large skull defect) was shown to augment the volume and the volume-increasing rate by 1.553 cm3, 0.101% (p less then 0.001) and 1.126 cm3, 0.072% (p less then 0.001), respectively, when compared to those in Group 1 (defect area less then 125 cm2). The volumetric augmentation achieved by contour elevation for an extremely large skull defect was smaller than that achieved for a large skull defect. Conclusions The 3D CAD skull
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