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Patients with carcinoma had larger nodules (average diameter 3.3 cm versus 2.5 cm, respectively, = .01), but no association with TI-RADS. Adults with nodules suspicious for HCN have significant risk of malignancy consistent with prior studies. Older males and larger nodule diameter are associated with malignancy in this cohort, but TI-RADS grade is not. These findings provide a framework for management and counseling for lesions suspicious for HCN. Adults with nodules suspicious for HCN have significant risk of malignancy consistent with

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