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How Does ADHD Medication Work? When sends an information to another, it makes use of neurotransmitters or chemicals. These chemicals must pass through the gap, which is known as a synapse. Some ADHD medications can make the passing along of these messages more efficient. They may help neurons release neurotransmitters more frequently or slow down the process of reuptake (called reuptake inhibiters). Doctors put patients suffering from ADHD on a low dose of medication and then observe their responses. They alter the dosage over time to determine the "sweet
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