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How Does ADHD Medication Work? When a neuron sends an information to another, it makes use of neurotransmitters, chemicals. They need to cross a tiny gap called the synapse. Some ADHD medications can increase the efficiency of these messages. They may help neurons release neurotransmitters more or slow the reuptake (called Reuptake inhibitors). Doctors put patients suffering from ADHD with a small dose of medication, and then monitor their responses. They gradually increase the dosage to find the "sweet spot," the lowest dose that shows a noticeable improvement i
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