https://www.selleckchem.com/pr....oducts/VX-680(MK-045
An increase in the expression of the CD34 antigen and other hematopoietic antigens were observed to 1% O with MSCs plus ECs and low ROS levels. These findings suggest that 3D-MS formed by MSCs, ECs and HSCs exposed to low concentrations of oxygen (1-3% O ) modulate human HSC behavior and mimics some features of the perivascular niche, which could reduce the use of animal models and deepen the relationship between the microenvironment of HSC and human hematological diseases development. These findings suggest that 3D-MS formed by
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