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Multiple regression analysis was performed. Multicollinearity was quantified using the variance inflation factor. In the 202 patients, serum level of ALP was the only independent factor that significantly affected both the number of non-inflammatory acne lesions and of total acne lesions (regression coefficient=0.089 and 0.086, respectively, 0.001). There was a significant correlation between serum level of ALP and the extent of acne (non-inflammatory acne lesions and total acne lesions). There was a significant correlation between s
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