https://www.selleckchem.com/products/bi-3812.html
The aggressive phenotype of fibroblast-like synoviocytes (FLSs) is essential in the synovitis and bone destruction in rheumatoid arthritis (RA). Punicalagin is a natural polyphenol extracted in pomegranate juice, which possesses antioxidant, anti-inflammatory and anti-tumor properties suggesting it may be a potent drug for RA therapy. However, there is paucity of information on its effect in RA. To investigate the effects of punicalagin on synovial inflammation and bone destruction in RA. FLSs were isolated from synovial tissue of RA pa
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