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ADHD Medications - What Are the Side Effects? Many people with ADHD are treated with medication. It can improve symptoms but it also can cause negative side effects. If you experience any adverse effects, speak to your GP about them. Stimulants are the most common type of prescription medication healthcare doctors prescribe to treat ADHD. These drugs increase the amount of brain chemicals known as neurotransmitters, that regulate the behavior and attention. Methylphenidate Methylphenidate, a stimulant