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How Does Medication For ADHD Work? Stimulants can improve your ability to focus and control impulses by increasing the levels dopamine and norepinephrine within your brain. They are available in immediate-release (short acting) and extended release tablets. They can be taken daily in the morning. Nonstimulant medications can help improve the ability to control impulses and attention however, they require more time to work. Atomoxetine, Viloxazine and guanfacine are antidepressants that b