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Our studies propose Baicalin and Limonin in combination to be studied in vitro and in vivo against COVID-19. Communicated by Ramaswamy H. Sarma.Fecal microbial community changes are associated with numerous disease states, including cardiovascular disease (CVD). However, such data are merely associative. A causal contribution for gut microbiota in CVD has been further supported by a multitude of more direct experimental evidence. Indeed, gut microbiota transplantation studies, specific gut microbiota-dependent pathways, and downstream met