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Data revealed that 7 in vivo up-regulated genes were involved in virulence, and could be considered new therapeutic targets. This study provides an insight into the A. baumannii gene expression profile during the murine pneumonia infection. Data revealed that 7 in vivo up-regulated genes were involved in virulence, and could be considered new therapeutic targets. Despite the progress made in studying protein-ligand interactions and the widespread application of docking and affinity prediction tools, improving their precision and efficie