https://www.selleckchem.com/pr....oducts/shp099-dihydr
Results We found that LPS-induced microglia activation correlates with detected changes in NADH lifetime and its free-bound ratio. This indicates that NADH lifetime can be used to monitor microglia activation in a label-free fashion. Moreover, we found that there is an LPS dose-dependent change associated with reactive microglia lifetime fluxes, which is also replicated over time after LPS treatment. Conclusion We have demonstrated a label-free way of monitoring microglia activation via quantifying lifetime of endogenous
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