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and sleep. Prospectively registered with PROSPERO International Prospective Register of Systematic Reviews (CRD42018091647). Prospectively registered with PROSPERO International Prospective Register of Systematic Reviews (CRD42018091647). Many articles published in the neurosurgical literature make claims of safety regarding interventions. The strength of evidence supporting these claims has not been systematically evaluated. To evaluate the quality of evidence supporting claims of safety in the neurosurgery literature. The 14 neurosur
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