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Constructing bioactive materials remains a big challenge through the aggregates of molecules. Herein, a boron dipyrromethene (BODIPY) derivative containing three nitro groups (BDP-(NO2)3) was synthesized, which displays the characteristic of J-aggregate with pronounced red-shifted absorption in nonpolar solvent and aqueous media. The bathochromic shift from 635 to 765 nm facilitates photothermal transition upon the irradiation of near-infrared (NIR) light. Interestingly, BDP-(NO2)3 nanoparticles (NPs) fabricated from BDP-(NO2)3 and poly

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