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on recognition and processing tasks as key cognitive markers of this neurodegenerative syndrome. The volume loss of the hippocampus and amygdala in non-demented individuals has been reported to increase the risk of developing Alzheimer's disease (AD). Many neuroimaging genetics studies mainly focused on the individual effects of APOE and CLU on neuroimaging to understand their neural mechanisms, whereas their synergistic effects have been rarely studied. To assess whether APOE and CLU have synergetic effects, we investigated the epistat
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