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A dual-function cellulose nanofiber (CNF)-based bionic biosensor with good biocompatibility was developed for detecting Ag+ and acetylcholinesterase (AChE) by grafting deoxyribonucleic acid (DNA) onto CNF. The Ag+ ions captured by the biosensor acted as recognition sites for the detection of AChE. The CNF-based bionic biosensor (CNF-DNA) could detect Ag+ concentrations as low as 10-6 nM in the presence of interference metal ions (Hg2+, Ba2+, Cd2+, Mg2+, Mn2+, Pb2+, and Zn2+). DNA-template silver nanoclusters (DNA-AgNCs) were formed on th
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