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Sleep is a unique behavioral state that affects body functions and memory. Although previous studies suggested stimulation methods to enhance sleep, a new method is required that is practical for long-term and unconstrained use by people. In this study, we used a novel closed-loop vibration stimulation method that delivers stimulus in interaction with the intrinsic heart rhythm and examined the effects of stimulation on sleep and memory. Twelve volunteers participated in the experiment and each underwent one adaptation night and two exper