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We conclude that 2H2O-method can be used to study metabolically controlled histone acetylation and acetylated histone turnover in vivo. Reduced minimal erythema dose (MED) is an abnormal erythematous reaction to light according to the skin phototype, which is determined by phototest. MED is reduced or abnormal in some photodermatoses. However, we have not found information about reduced MED in patients with solar urticarial (SU), a condition which causes hives after sun exposure. To determine MED in a series of patients with SU. We con