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6 ± 8.6 days vs. 10.8 ± 7.9 days; P=0.008). IEAT was an independent risk factor for longer LOS along with aCCI score ≥2, lung disease and cardiac disease. Empirical use of fluoroquinolones for UTIs should be avoided, especially in male patients with aCCI score 6. Improved empirical antimicrobial therapy may have a beneficial impact in reducing bacterial resistance and healthcare costs by decreasing the LOS. Therefore, interventions to promote in-depth antibiotic stewardship programmes in China are needed. 6. Improved empirical antimi