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ADHD Treatment Medication Adults with ADHD are usually treated with psychosocial therapy and medications. The medications used to treat ADHD can include stimulants and nonstimulants. Stimulants like methylphenidate and Lisdexamfetamine affect chemical messengers in the brain to boost mood, concentration, and impulse control. Atomoxetine, or guanfacine both of which are non-stimulant ADHD medications, can be prescribe