https://www.selleckchem.com/pr....oducts/Hesperadin.ht
The etiology of sporadic Alzheimer's disease (AD) requires non-genetically modified animal models. The relationship of tau phosphorylation to calcium-cyclic adenosine monophosphate (cAMP)-protein kinase A (PKA) dysregulation was analyzed in aging rhesus macaque dorsolateral prefrontal cortex (dlPFC) and rat primary cortical neurons using biochemistry and immuno-electron microscopy. The influence of calcium leak from ryanodine receptors (RyRs) on neuronal firing and cognitive performance was examined in aged macaques. Aged monkeys nat
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