https://www.selleckchem.com/pr....oducts/cucurbitacin-
Both nitric oxide (NO) and serotonin (5HT) mediate swim acceleration in the marine mollusk, Clione limacina. In this study, we examine the role that the second messenger, cyclic guanosine monophosphate (cGMP), plays in mediating NO and 5HT-induced swim acceleration. We observed that the application of an analog of cGMP or an activator of soluble guanylyl cyclase (sGC) increased fictive locomotor speed recorded from Pd-7 interneurons of the animal's locomotor central pattern generator. Moreover, inhibition of sGC decreased fictive
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