https://www.selleckchem.com/pr....oducts/Cyclopamine.h
Mitochondrial biogenesis is indispensable for organismal homeostasis. The semi-autonomous nature of mitochondria renders their biogenesis rather complex, as it requires the contribution of the nucleus, the cytoplasm and the organelle itself. Recently, several transcription regulators, RNA binding proteins and outer mitochondrial membrane (OMM) components have been implicated in the coordination of the process. Both the expression and the abundance of several of these factors are altered during ageing, and their impairment can have d
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