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s. All rights reserved. For permissions, please e-mail [email protected] Evidence to inform cryptococcal antigen (CrAg)-screening guidelines among antiretroviral therapy (ART)-experienced populations are lacking. We performed a study evaluating the utility of reflex CrAg-screening in Gaborone, Botswana. METHODS CD4 count data were collected from samples tested at the HIV reference laboratory from 2014-2016. CrAg screening was performed on samples with CD4 ≤100 cells/µL beginning January 2015. The proportion of CD4

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