https://ak7inhibitor.com/?p=2126preview=true
Only a tiny proportion of person eRNA loci was specifically identified, limiting investigations of enhancer-mediated oncogenic systems. Here, we characterize super-enhancer regions using aggregated RNA sequencing (RNA-seq) data from huge cohorts. Super-enhancers frequently have discrete loci featuring sharp eRNA expression peaks. We identify 300,000 eRNA loci in ∼377 Mb super-enhancer areas being managed by evolutionarily conserved, well-positioned nucleosomes consequently they are frequently dysregulated in cancer tumors. The eRNAs
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